💛 Poppy Grace — The Little Girl Who Lit Every Room She Entered 💛
She was only 11 weeks old when the word leukaemia entered her world — a word no parent should ever have to hear.
But from that very first moment, baby Poppy Grace showed a strength that stunned even her doctors.
She smiled through pain, laughed through exhaustion, and made sure everyone around her felt seen and loved.
Her mums, Carly and Tresne, often said that she had “an old soul — one that understood more about life than most adults ever will.”
This is her story.
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🌸 The First Signs
At her six-week vaccinations, the nurse noticed a small bruise on Poppy’s thigh.
“It’s probably nothing,” she said gently, “but get it checked just to be safe.”
Carly and Tresne didn’t worry much — babies bruise easily. Still, they took her to the family GP, who ordered an ultrasound.
The results came back clear. Just a bruise, the report said.
But in hindsight, that tiny mark was a warning — one of the earliest signs of low platelets, a symptom of childhood leukaemia.
Over the next few weeks, Poppy became restless. She struggled to sleep, cried often, and couldn’t seem to get comfortable.
Her parents, first-time mums, assumed it was colic or teething.
Then, one night, Poppy began vomiting violently — projectile vomiting, over and over again.
That’s when they knew something was wrong.
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💔 A Shocking Diagnosis
At the hospital, the paediatrician immediately noticed that Poppy was extremely pale and her belly was unusually swollen.
He ordered blood tests and an ultrasound.
Within an hour, he returned — his expression grave.
“Her white blood cell count is extremely high. Her spleen is enlarged. And her haemoglobin is dangerously low — just 23.”
Carly and Tresne’s hearts stopped.
For reference, a healthy baby’s haemoglobin should be above 95.
That Poppy was even awake, breathing, and responsive was nothing short of miraculous.
The doctor handed them a letter and told them to go straight to the
John Hunter Oncology Unit.
Due to COVID-19 restrictions, only one parent was allowed to enter.
Carly ran inside with Poppy while Tresne sat outside in tears, begging the staff to let her in.
Finally, after several calls, she was allowed to join them.
Inside, doctors struggled for half an hour to draw blood — it was so thick from cancer cells that it came out like syrup.
They rushed Poppy to surgery to insert an emergency IV line into her neck.
The doctors warned her mothers that she might not survive the operation.
But Poppy did.
Because that’s who she was — a fighter from the very beginning.
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🩸 High-Risk and Rare
In the Paediatric Intensive Care Unit, Poppy was diagnosed with High-Risk Infantile Acute Lymphoblastic Leukaemia (ALL) —
a form so rare that only five or six babies in Australia are diagnosed each year.
Her survival odds were only 20%, made even slimmer by what her doctors called “the trifecta”:
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She was under six months old.
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Her white blood cell count was over 150.
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She carried the MLL gene mutation, associated with highly aggressive leukaemia.
Her mums were devastated.
They had waited years to hold their miracle baby — and now, she was fighting for her life.
“Those first days felt like a blur,” Carly said. “We were living minute to minute, terrified to sleep in case something happened.”
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🌈 Treatment and the Long Road Home
After 48 hours in intensive care, Poppy was transferred to
J1 Paediatric Oncology Ward,
the place that would become her second home for the next
13 months.
Doctors took samples from her bone marrow and sent them to the Zero Childhood Cancer (ZERO) research team —
a national program that uses genetic testing to identify which chemotherapy drugs might work best for each child.
Over the months that followed, Poppy endured unimaginable treatment:
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547 days of active therapy
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129 rounds of chemotherapy
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113 blood transfusions
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37 lumbar punctures
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9 CT scans, 6 MRIs, and countless injections and procedures
And through it all, she smiled.
“She would look straight into your eyes and beam,” said one nurse. “It didn’t matter how sick she was — she always found joy.”
Her first round of immunotherapy gave her a brief reprieve. For a few precious weeks, she was able to go home.
But just as she began to laugh and play again, her cancer relapsed.
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⚔️ Relapse and Relentless Hope
The relapse was devastating.
Poppy spent eight more weeks in intensive care battling complications — mucositis, chemotoxicity, constant vomiting.
Her tiny body was breaking, but her spirit wasn’t.
“She’d still try to dance in her bed,” Carly recalled. “Even hooked up to machines, she’d sway to music.”
After a bone marrow transplant — her last major chance at a cure — Poppy’s family dared to hope again.
But 56 days later, just after her first birthday, the leukemia returned.
Doctors said they had never seen it relapse so quickly after transplant.
There was nothing more they could do.
They told Carly and Tresne to take her home and make memories.
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💫 Fighting Until the End
Unwilling to give up, the family reached out to the world through social media.
They asked if anyone — anywhere — knew of a treatment that could help.
Messages poured in from around the globe: doctors, nurses, parents, researchers.
One suggestion appeared again and again — CAR-T cell therapy, an experimental treatment that teaches the immune system to fight cancer itself.
Meanwhile, results from the ZERO team offered a glimmer of hope:
Poppy’s cancer cells were sensitive to Venetoclax, a new trial drug.
On compassionate grounds, doctors secured access — and it worked.
The medication helped keep her leukemia under control, giving her months more than anyone thought possible.
But Poppy’s immune system was too weak for CAR-T therapy. Her T cells never recovered enough to proceed.
Still, she lived her final months surrounded by laughter and love.
She danced to Christmas music, read Hey Duggee books, and giggled at her mums’ silly faces.
At 4:20 a.m. on February 16, 2023, her brave little heart finally rested.
She was 20 months old.
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🕊 Her Light Lives On
In her short but extraordinary life, Poppy Grace inspired thousands.
She showed the world what courage looks like — not in grand gestures, but in small acts of joy in the face of pain.
“She smiled at everyone,” said Tresne. “She made eye contact with strangers and made them feel seen. That was her gift.”
Today, her legacy continues through her parents’ advocacy and the research she helped advance.
Carly and Tresne now dedicate their time to fundraising for Children’s Cancer Institute, supporting the search for targeted treatments for infant leukemia — so that one day, no child will have to endure what Poppy did.
They also encourage everyone to donate blood in her honour.
Because blood donations kept their daughter alive for 547 days —
547 days of laughter, dancing, love, and light.
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💛 Poppy Grace’s story reminds us that even the smallest souls can leave the brightest legacies.
Her time on earth was brief, but her impact will ripple through generations — in every drop of blood donated,
in every new discovery that saves another child’s life,
and in every smile that shines through the darkness.